New Publication Alert!
We’re excited to share our latest research:
“Rational design of a small peptidomimetic ligand to capture a viral spike protein” 🧪
This study presents the design of a synthetic affinity adsorbent capable of capturing and purifying the SARS-CoV-2 spike protein in a single step — with over 95% binding efficiency and up to 73% recovery across multiple variants.
By screening a 120-ligand library through computational and experimental approaches, and uncovering key hydrophobic and electrostatic interactions via molecular dynamics, we highlight a fast and robust platform for purification tool development in future pandemics.
Check the full article:
https://www.sciencedirect.com/science/article/pii/S1383586625013759
